The reason you are likely receiving this issue is that SQLCipher for Android is only built for armeabi, armeabi-v7a, and x86 platforms. You are likely deploying to a x86_64 device so Android uses the corresponding folder for resolving all native libraries (i.e., x86_64), as such the SQLCipher for Android binaries are not present in your x86_64 folder. A work around is to remove the x86_64 native libraries entirely, it should fall back to x86 folder for x86_64 devices.