Hello @sammacdougall
There are a couple of resources you might want to review. First, there are some major changes in the latest SQLCipher 4 series that you should be aware of. We cover migration of database file formats here. Next, we have a write up that covers upgrading the client libraries from the 3.x series to the new 4.x series here. Finally, we have steps for setting up the a new project which includes Xamarin here. Would you review those links and and let us know if you have any additional questions? Thanks!