@srinivas3120 as @developernotes mentioned on the Github ticket you opened, here isn’t a simple way to reduce the size. You can consider removing native platforms to reduce the number of binary objects that have to be included with the APK (e.g. remove x86, since libhoudini should allow the arm binaries to be used). For example, if you are manually packaging SQLCipher, only include the armeabi and armeabi-v7a folders and binaries. Or, if you are using gradel, include an abiFilter in the gradle configuration, e.g.
abiFilters "armeabi", "armeabi-v7a"
If that doesn’t reduce the size enough you will need to reconsider using SQLCipher to provide your application with local data encryption.